Research
Evolutionary biology, genomics, and environment.
Mission
Creating an inclusive research environment where everyone is valued and empowered to conduct high quality research.
Vision
We aspire to become a world-class evolutionary genomics lab and address fundamental biological questions with innovative technologies and methodology.
Origin of obligate parthenogenesis
We explore the genetic mechanisms giving rise to obligately parthenogenetic Daphnia, including incompatibility between D. pulex and D. pulicaria.
Evolution of meiotic recombination rate
We investigate genetic variants regulating recombination-rate variation using single-sperm whole-genome sequencing, population genomics, and CRISPR-Cas editing.
CRISPR gene editing
Our lab develops gene knock-out, gene knock-in, and precise base-editing methods for Daphnia to study gene function and interactions.
Environmental mutagens and genomic integrity
We study how environmental mutagens such as EMS affect mutation rates, mutation spectra, and gene expression in Daphnia.
Genetic incompatibility and postzygotic reproductive isolation
We investigate how incompatible allele combinations between diverged Daphnia lineages impair hybrid development and fitness, revealing the genetic basis of postzygotic reproductive barriers.
Single-nucleus transcriptomics and chromatin accessibility
We use single-nucleus RNA-seq and ATAC-seq to characterize cell-type-specific gene expression and chromatin accessibility in Daphnia.
Centromere and kinetochore genomics
We map centromeric regions and kinetochore-associated features to investigate chromosome segregation, genome organization, and chromosome evolution.
